Science Magazine Login The weight-loss drugs are ultimately drugs for the brain. Obesity medications differ in a key way from the natural molecule they're meant to mimic: They last a lot longer. GLP-1 released in the ... Millions of research papers at risk of disappearing from the Internet In the fourth century, the Greek mathematician Pappus of Alexandria praised bees for their "geometrical forethought." The hexagonal structure of their honeycomb seemed like the optimal way to partition two-dimensional space into cells of equal area and minimal perimeter — allowing the insects to cut down on how much wax they needed to produce, and to spend less time and energy building ... Even a 2°C drop in the core body temperature can cause hypothermia. At this point, the effects of cold on the brain are most apparent. "At 18°C, we'll have a massive leak in our blood-brain barrier, and the brain is not protected anymore from the normal junk we produce," Gracheva said. 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